Initiating carcinogen, triethylenemelamine, induces micronuclei in skin target cells

Morphological and functional alterations

Morphological and functional alterations in human proximal tubular cell line induced by low level inorganic arsenic: evidence for targeting of mitochondria and initiated apoptosis

✍ Marjorie A. Peraza; Douglas W. Cromey; Barb Carolus; Dean E. Carter; A. Jay Gand 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 511 KB

The kidney is a known target organ for arsenic and is critical for both arsenic biotransformation and elimination. Previous studies have demonstrated that at high doses (ppm) inorganic arsenic is toxic to mitochondria primarily by affecting cellular respiration. However, the effect of inorganic arse