Initial treatment in multiple myeloma: no advantage of multidrug chemotherapy over melphalan-prednisone
✍ Scribed by Martin Hjorth; Louise Hellquist; Erik Holmberg; Bengt Magnusson; Stig Rödjer; Jan Westin; for the Myeloma Group of Western Sweden
- Book ID
- 114712003
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 633 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0007-1048
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## METHODS. Four hundred seventy-nine previously untreated patients with multiple myeloma from 23 ECOG institutions were enrolled. Treatment, assigned by ran-1 The Virginia Piper Cancer Institute and the Unidomization, consisted of either 4-week cycles of MP or 5-week cycles of VBCMP.
## Abstract A study was designed to evaluate the effectiveness of prednisone therapy in poor‐risk patients with multiple myeloma. Patients were treated with melphalan alone or in combination with prednisone at doses of either 0.6 mg/kg or 0.3 mg/ kg. The group of patients receiving melphalan and pr