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Initial slope technique for estimation of the apparent volume of distribution during constant-rate intravenous infusion

โœ Scribed by Joseph F. Cocchetto; David M. Cocchetto; Thorir D. Bjornsson; Tom Bergan


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
562 KB
Volume
73
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES


Area-based estimation of the initial vol
โœ Soo Peang Khor; Stephen L. Johnson; Michael Mayersohn ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 758 KB

We evaluate here an area term, the area under the rate of change of concentration-time curve (AURC), which allows the determination of the initial or central volume of distribution (V1). It has previously been shown that AURC is equal to the sum of the coefficients of a multiexponential equation and