Initial experience with a multimodal enhanced recovery programme in patients undergoing liver resection
โ Scribed by R. M. van Dam; P. O. Hendry; M. M. E. Coolsen; M. H. A. Bemelmans; K. Lassen; A. Revhaug; K. C. H. Fearon; O. J. Garden; C. H. C. Dejong
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 125 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0007-1323
- DOI
- 10.1002/bjs.6227
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โฆ Synopsis
Abstract
Background
Accelerated recovery from surgery has been achieved when patients are managed within a multimodal Enhanced Recovery After Surgery (ERAS) protocol. This study evaluated the benefit of an ERAS programme for patients undergoing liver resection.
Methods
The ERAS protocol of epidural analgesia, early oral intake and early mobilization was studied prospectively in a consecutive series of 61 patients. Outcomes were compared with those in a consecutive series of 100 patients who underwent liver resection before the start of the study. Endpoints were postoperative length of hospital stay, postoperative resumption of oral intake, readmissions, morbidity and mortality.
Results
Fifty-six patients (92 per cent) in the ERAS group tolerated fluids within 4 h of surgery and a normal diet on day 1 after surgery. Median hospital stay, including readmissions, was 6ยท0 days compared with 8ยท0 days in the control group (P < 0ยท001). There were no significant differences in rates of readmission (13 and 10ยท0 per cent respectively), morbidity (41 and 31ยท0 per cent) and mortality (0 and 2ยท0 per cent) between ERAS and control groups.
Conclusion
The ERAS fast-track protocol is safe and effective for patients undergoing liver resection. It allows early oral intake, promotes faster postoperative recovery and reduces hospital stay.
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