Since single drug therapy of chronic lymphocytic leukemia (CLL) has not resulted in prolonged remissions of advanced disease, we initiated a program of combination chemotherapy, COP (cycloposphamide, vincristine sulfate, prednisone) for CLL patients with increasing adenopathy, splenomegaly, and/or s
✦ LIBER ✦
Initial chemotherapy for chronic lymphocytic leukemia: What’s the standard of care?
✍ Scribed by Matt Kalaycio
- Book ID
- 107540142
- Publisher
- Current Science Inc.
- Year
- 2006
- Tongue
- English
- Weight
- 65 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1558-8211
No coin nor oath required. For personal study only.
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For many years it has been evident that B-cell chronic lymphocytic leukemia (CLL) displays preferential usage of individual immunoglobulin (Ig) variable heavy chain (V(H)) genes. The V(H)1-69 gene was the first to be reported overrepresented in a large number of CLL patients, where the V(H)1-69(+) C