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Inhibitory Receptor Signaling via Tyrosine Phosphorylation of the Adaptor Crk

✍ Scribed by Mary E. Peterson; Eric O. Long

Book ID
116570880
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
561 KB
Volume
29
Category
Article
ISSN
1074-7613

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## Abstract Most insulin responses correlate well with insulin receptor (IR) Tyr kinase activation; however, critical exceptions to this concept have been presented. Specific IR mutants and stimulatory IR antibodies demonstrate a lack of correlation between IR kinase activity and specific insulin r