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Inhibitory Effects of Various Extracts of Argentine Plant Species on Free-radical-mediated Reactions and Human Neutrophil Functions

✍ Scribed by M. Payá; M. Silla; E. Vayá; M. J. Alcaraz; J. Coussio; G. Ferraro; V. Martino; O. Hnatyszyn; S. Debenedetti; A. Broussalis; L. Muschietti


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
464 KB
Volume
10
Category
Article
ISSN
0951-418X

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✦ Synopsis


Extracts of Argentine plant species used in folk medicine were evaluated for their antioxidant properties and ability to influence human neutrophil functions, including superoxide anion release and degranulation. The infusion and methanol extract of Achyrocline jlaccida, and the infusion of Pterocaulon polystachium exhibited chain-breaking antioxidant activity in Fe**/ascorbate-induced lipid peroxidation of rat liver microsomal fractions and scavenged peroxyl radicals in an aqueous assay system. Nevertheless their superoxide scavenging ability was lower. The dichloromethane extracts of Phyllanthus sellowianus, Achyrocline jlaccida, Gamochaeta simplicicaulis, Pterocaulon polystachium and Eupatonum buniifolium, besides the infusion of Eupatorium buniifolium and the methanol extract of Pterocaulon polystachium, inhibited neutrophil functions.