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Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3

โœ Scribed by Haruka Nishimuta; Hisakazu Ohtani; Masayuki Tsujimoto; Kenichiro Ogura; Akira Hiratsuka; Yasufumi Sawada

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
175 KB
Volume
28
Category
Article
ISSN
0142-2782

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## Abstract Cigarette smoke contains polycyclic hydrocarbons and arylamines that may both be activated by sulfotransferase, encoded by __SULT1A1__. A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association betwe