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Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor γ ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide

✍ Scribed by Koujiro Yoshida; Yoshinobu Hirose; Takuji Tanaka; Yasuhiro Yamada; Toshiya Kuno; Hiroyuki Kohno; Masaki Katayama; Zheng Qiao; Keiko Sakata; Shigeyuki Sugie; Toshiyuki Shibata; Hideki Mori


Book ID
108582274
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
554 KB
Volume
94
Category
Article
ISSN
1347-9032

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## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid