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Inhibitory effects of some derivatives of glycyrrhizic acid against Epstein-Barr virus infection: Structure–activity relationships

✍ Scribed by Jung-Chung Lin; Jaw-Ming Cherng; Man-Shan Hung; Lidia A. Baltina; Lia Baltina; Rimma Kondratenko

Book ID
113457817
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
935 KB
Volume
79
Category
Article
ISSN
0166-3542

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New derivatives of (-)-indolactam V (Fig. 1), which have the basic ring-structure of teleocidins without the monoterpenoid moiety, were prepared and their Epstein-Barr virus early antigen (EBV-EA)-inducing activity was tested. (-)-14-O-Alkyl indolactam Vs (2 and 3) showed little induction of EBV-EA,