## Abstract Little is known about the biological effects of bisphosphonates on primary malignant bone tumors. The purpose of this study was to investigate the antitumor effects of newly developed minodronate (MIN) on a variety of human malignant bone tumors. We examined the effects of MIN and clini
Inhibitory effects of phenylbutyrate on the proliferation, morphology, migration and invasiveness of malignant glioma cells
โ Scribed by Herbert H. Engelhard; Ronald J. Homer; Holly A. Duncan; Jack Rozental
- Book ID
- 110229952
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 566 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0167-594X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Background and Objective: High-grade gliomas are characterized by rapid proliferation, angiogenesis, and invasive growth. Eradication or inhibition of infiltrating glioma cells poses a significant clinical challenge that is unlikely to be solved using conventional treatment regimens consisting of io
Glioma invasion into the surrounding brain tissue is still a major obstacle for any therapeutical approach. As in other solid tumors, matrix-metalloproteases (MMPs) have been suggested as being involved. The aim of this study was to evaluate whether the use of MMP inhibitors to target the protease-m
## Abstract ## Background Because of the known property of less aggressiveness of differentiated cells compared to immatured cells all attempts are made to elucidate whether differentiation inducers possibly could be applied for neuroblastoma therapy. We are interested in examining the influence o