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Inhibitory effects of melittin on the production of lipopolysaccharide-induced matrix metalloproteinase 3 in human osteoarthritic chondrocytes

✍ Scribed by Seong-Su Nah; Eunyoung Ha; Hye-Jung Lee; Joo-Ho Chung

Book ID
116921742
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
165 KB
Volume
49
Category
Article
ISSN
0041-0101

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## Abstract ## Objective To investigate the effects of prostaglandin D~2~ (PGD~2~) on interleukin‐1Ξ² (IL‐1Ξ²)–induced matrix metalloproteinase 1 (MMP‐1) and MMP‐13 expression in human chondrocytes and the signaling pathways involved in these effects. ## Methods Chondrocytes were stimulated with I