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Inhibitory effects of melatonin on vascular reactivity: possible role of vasoactive mediators

✍ Scribed by Mamdouh M. Anwar; Abdel-Raheim M.A. Meki; Hassan H. Abu Rahma


Book ID
117794252
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
167 KB
Volume
130
Category
Article
ISSN
1532-0456

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SUMMARY: The influence of melatonin on tension of isolated pulmonary vascular smooth muscle rings was examined in these experiments. Melatonin caused a dose-dependent relaxation of precontracted \((30 \mathrm{mM} \mathrm{KCl})\) pulmonary artery and pulmonary vein. Removal of the endothelium did not