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Inhibitory Effects of Cigarette Smoke on Glial Inducible Nitric Oxide Synthase and Lack of Protective Properties Against Oxidative Neurotoxins In Vitro

✍ Scribed by Elizabeth A. Mazzio; Malak G. Kolta; R. Renee Reams; Karam F.A. Soliman

Book ID
116779519
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
549 KB
Volume
26
Category
Article
ISSN
0161-813X

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## Abstract The inhibitory effects of inotilone and methylinotilone on the induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase‐2 (COX‐2) in murine RAW 264.7 cells activated with LPS were investigated. The results show that both hydroxyl groups on the benzene ring of the inotilone