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Inhibitory Effects of an Antisense Oligonucleotide in an Experimentally Infected Mouse Model of Influenza A Virus

✍ Scribed by Tadashi Mizuta; Masatoshi Fujiwara; Takayuki Abe; Naoko Miyano-Kurosaki; Tomoyuki Yokota; Shiro Shigeta; Hiroshi Takaku

Book ID
115587001
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
42 KB
Volume
279
Category
Article
ISSN
0006-291X

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## Abstract A mouse model study using mouse brain‐adapted influenza A virus was performed to establish the prophylaxis and treatment of influenza encephalitis and encephalopathy. All mice died after intranasal inoculation of the brain‐adapted influenza A virus (H7N3), and the pathological findings