Inhibitory effects of AMP 579, a novel cardioprotective adenosine A1/A2Areceptor agonist, on nativeIKrand cloned HERG current

Pharmacological characterization of AMP

Pharmacological characterization of AMP 579, a novel adenosine A1/A2 receptor agonist and cardioprotective

✍ Linda Merkel; Camilo J. Rojas; Michael F. Jarvis; Bryan F. Cox; Cynthia Fink; Gl 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 302 KB 👁 1 views

2β,3β,4α(S\*) ]-4-[7- [[1-[(3-chloro-2-thienyl)methyl]propylamino]-3Himidazo [4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxy cyclopentanecarboxamide) is a novel cardioprotective adenosine agonist with the following order of affinity at adenosine receptors: A 1 > A 2A > A 3 . Agonism at A 1 receptors was