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Inhibitory effect of the plant-extract osthole on L-type calcium current in NG108-15 neuronal cells

โœ Scribed by Sheng-Nan Wu; Yuk-Kang Lo; Chien-Chich Chen; Hui-Fang Li; Hung-Ting Chiang

Book ID
113992897
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
224 KB
Volume
63
Category
Article
ISSN
0006-2952

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Differential effects of quercetin, a natural polyphenolic flavonoid, on L-Type calcium current in pituitary tumor (GH3) cells and neuronal NG108-15 cells
โœ Sheng-Nan Wu; Hung-Ting Chiang; Ai-Yu Shen; Yuk-Keung Lo ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 264 KB

The effects of quercetin, a natural polyphenolic compound, on voltage-dependent L-type Ca(2+) current (I(Ca,L)) in rat pituitary GH(3) cells were investigated with the aid of the whole-cell voltage-camp technique. Quercetin (0.5-200 microM) stimulated I(Ca,L) in a concentration-dependent manner. The