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Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils

✍ Scribed by Takeshi Toyoda; Tetsuya Tsukamoto; Tsutomu Mizoshita; Sansei Nishibe; Takeshi Deyama; Yoshiharu Takenaka; Naoki Hirano; Harunari Tanaka; Shinji Takasu; Hisayo Ban; Toshiko Kumagai; Ken-ichi Inada; Hirotoshi Utsunomiya; Masae Tatematsu

Book ID: 108584001
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 227 KB
Volume: 98
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2007.00599.x

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## Abstract Nuclear factor‐κB (NF‐κB) plays a major role in host inflammatory responses and carcinogenesis and as such is an important drug target for adjuvant therapy. In this study, we examined the effect of caffeic acid phenethyl ester (CAPE), an NF‐κB inhibitor, on __Helicobacter pylori__ (__H.