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Inhibitory effect of genistein on agonist-induced modulation of vascular contractility

✍ Scribed by Hyun Dong Je; Uy Dong Sohn

Book ID
106262914
Publisher
Korean Society for Molecular and Cellular Biology
Year
2009
Tongue
English
Weight
674 KB
Volume
27
Category
Article
ISSN
1016-8478

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Effect of Modulators of Tyrosine Kinase
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In the rat isolated main pulmonary artery, we investigated the effect of a tyrosine kinase inhibitor (genistein) and that of a tyrosine phosphatase inhibitor (phenylarsine oxide) on agonist-induced contraction. Genistein (10 microM) reduced the amplitude of the contraction evoked by noradrenaline (0