Inhibitory effect of foetal α2 globulin, an acute phase protein, on carrageenin oedema in the rat

Inhibition of long-term potentiation dev

Inhibition of long-term potentiation development in rat hippocampal slice by α2-macroglobulin, an acute-phase protein in the brain

✍ I. Çavuş; P.H. Koo; T.J. Teyler 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 690 KB

Alpha-2-macroglobulin (a,M) in the rat and human brain is an acute-phase protein synthesized primarily by astrocytes, and it has been implicated in Alzheimer's disease and other neuropathological processes. The activated forms of aZM, but not the native form, can suppress the neurite outgrowth of th