Inhibitory effect of bombesin/gastrin-releasing peptide (GRP) antagonists RC-3950-II and RC-3095 on MCF-7 MIII human breast cancer xenografts in nude mice
✍ Scribed by Shirahige, Y.; Cai, R.-Z.; Szepeshazi, K.; Halmos, G.; Pinski, J.; Groot, K.; Schally, A.V.
- Book ID
- 123568460
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 725 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0753-3322
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## Abstract Nude mice bearing xenografts of the androgen‐independent human prostate‐cancer cell line PC‐3 were treated for 4 weeks with somatostatin analog RC‐160, bombesin/gastrin‐releasing peptide (GRP) antagonist (RC‐3095), or the combination of both peptides. In the first experiment, treatment
## Abstract Nude mice bearing xenografts of the gastrin‐responsive human gastric carcinoma MKN45 cell line were treated for 4 to 5 weeks with bombesin/gastrin‐releasing‐peptide(GRP) antagonist (RC‐3095), somatostatin analogues RC‐160 and SMS 201‐995, or the combination of RC‐3095 and RC‐160. Tumor