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Inhibitory effect of acetylsalicylic acid on matrix metalloproteinase - 2 activity in human endothelial cells exposed to high glucose

✍ Scribed by Manuela Nicolae; Magdalena Tircol; Dorin Alexandru

Book ID: 114778136
Publisher: Carol Davila University of Medicine Bucharest, Romania
Year: 2005
Tongue: English
Weight: 299 KB
Volume: 9
Category: Article
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2005.tb00391.x

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## Abstract Diabetes mellitus (DM) is a major risk factor for atherosclerosis and causes multiple cardiovascular complications. Although high glucose can induce matrix metalloproteinases (MMPs), its inhibitors and cell apoptosis, little is known about the roles of MMPs in regulating cell apoptosis