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Inhibitors of the γ-aminobutyric acid transporter 1 (GAT1) do not reveal a channel mode of conduction

✍ Scribed by Edward Matthews Jr.; Ali Rahnama-Vaghef; Sepehr Eskandari


Book ID
116765352
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
529 KB
Volume
55
Category
Article
ISSN
0197-0186

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Activation of γ-aminobutyric acid GAT-1
✍ Luca Raiteri; Sara Stigliani; Laura Patti; Cesare Usai; Giovanna Bucci; Alberto 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB

## Abstract The effects of γ‐aminobutyric acid (GABA) on the release of glutamate from mouse spinal cord nerve endings have been studied using superfused synaptosomes. GABA elicited a concentration‐dependent release of [^3^H]D‐aspartate ([^3^H]D‐ASP; EC~50~ = 3.76 μM). Neither muscimol nor (–)baclo