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Inhibitors of the anaplastic lymphoma kinase

✍ Scribed by Mologni, Luca


Book ID
111887026
Publisher
Informa plc
Year
2012
Tongue
English
Weight
276 KB
Volume
21
Category
Article
ISSN
1354-3784

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## Abstract Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase (RTK) involved in the genesis of several human cancers; indeed, ALK was initially identified in constitutively activated and oncogenic fusion formsβ€”the most common being nucleophosmin (NPM)‐ALKβ€”in a non‐Hodgkin's lymphoma (N