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Inhibitors of signal peptide peptidase (SPP) affect HSV-1 infectivity in vitro and in vivo

✍ Scribed by Allen, Sariah J.; Mott, Kevin R.; Ghiasi, Homayon


Book ID
122287495
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
985 KB
Volume
123
Category
Article
ISSN
0014-4835

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## Abstract ## Background Although hundreds of different signal peptides have now been identified, few studies have examined the factors enabling signal peptides to augment secretion of mature proteins. Signal peptides, located at the N‐terminus of nascent secreted proteins, characteristically hav