Farnesyltransferase inhibitors versus Ra
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Jackson B Gibbs; Samuel L Graham; George D Hartman; Kenneth S Koblan; Nancy E Ko
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Article
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1997
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Elsevier Science
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English
β 803 KB
Over the past few years, the idea that farnesyl-protein transferase (FPTase) inhibitors might be effective antiproliferative/antitumor agents has been realized in studies of cultured cells and in rodent models of cancer. Most of the studies with FPTase inhibitors have focused on inhibiting the growt