𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibitors of Protein Kinases: CGP 41251, a Protein Kinase Inhibitor with Potential as an Anticancer Agent

✍ Scribed by Doriano Fabbro; Elisabeth Buchdunger; Jeannette Wood; Jürgen Mestan; Francesco Hofmann; Stefano Ferrari; Helmut Mett; Terence O’Reilly; Thomas Meyer

Book ID
114129544
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
239 KB
Volume
82
Category
Article
ISSN
0163-7258

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The protein kinase C inhibitor CGP 41251
The protein kinase C inhibitor CGP 41251, a staurosporine derivative with antitumor activity, reverses multidrug resistance
✍ Irene Utz; Susanne Hofer; Urs Regenass; Wolfgang Hilbe; Josef Thaler; Hans Gruni 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 818 KB

Multidrug resistance (MDR) is frequently associated with overexpression of a 170-kDa P-glycoprotein (Pgp). Data suggest altered protein kinase C (PKC) activity in cells expressing the multidrug-resistant phenotype. The staurosporine derivative CGP 4 I25 I, an experimental anticancer drug, has been s