✦ LIBER ✦

Inhibitors of polyamine biosynthesis. 3. (+-)-5-Amino-2-hydrazino-2-methylpentanoic acid, an inhibitor of ornithine decarboxylase

✍ Scribed by Abdel-Monem, Mahmoud M.; Newton, Nancy E.; Weeks, Charles E.

Book ID: 120428177
Publisher: American Chemical Society
Year: 1975
Tongue: English
Weight: 504 KB
Volume: 18
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00243a017

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibitors of polyamine biosynthesis VI:

Inhibitors of polyamine biosynthesis VI: 2,5-diamino-2-(cyanomethyl)pentanoic acid, a potential irreversible inhibitor of ornithine decarboxylase

✍ Mahmoud M. Abdel-Monem; Ezzat A. Mikhail 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB

(+/-)-2,5-Diamino-2-)cyanomethyl)pentanoic acid was obtained by the reaction of chloracetonitrile with the anion obtained by treatment of 3-(benzylideneamino)-2-piperidinone with sodium hydride, followed by hydrolysis in the presence of trifluoroacetic anhydride. The target compound was isolated as

(2R,5R)-6-heptyne-2,5-diamine, an extrem

(2R,5R)-6-heptyne-2,5-diamine, an extremely potent inhibitor of mammalian ornithine decarboxylase

✍ C. Danzin; P. Casara; N. Claverie; B.W. Metcalf; M.J. Jung 📂 Article 📅 1983 🏛 Elsevier Science 🌐 English ⚖ 372 KB

Revival of 2-(difluoromethyl)ornithine (

Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventive agent1

✍ Raul, F. 📂 Article 📅 2007 🏛 Portland Press 🌐 English ⚖ 66 KB

Reversible inhibition of rat liver regen

Reversible inhibition of rat liver regeneration by 1,3-diamino-2-propanol, an inhibitor of ornithine decarboxylase

✍ Kirsti Piik; Hannu Pösö; Juhani Jänne 📂 Article 📅 1978 🏛 Elsevier Science 🌐 English ⚖ 333 KB

The inhibition of induction of microsoma

The inhibition of induction of microsomal monooxygenase activity by 1,3-diamino-2-propanol, an inhibitor of ornithine decarboxylase

✍ Hannu Raunio; Olavi Pelkonen 📂 Article 📅 1979 🏛 Elsevier Science 🌐 English ⚖ 358 KB

Inhibition of alloantigen-induced cytoly

Inhibition of alloantigen-induced cytolytic T lymphocytes in vitro with (2R,5R)-6-heptyne-2,5-diamine, an irreversible inhibitor of ornithine decarboxylase

✍ Terry L. Bowlin; Gregory F. Davis; Brenda J. McKown 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 497 KB