Inhibitors of lipoxygenase have antiproliferative effects on P815 murine mastocytoma cells
β Scribed by Ralph, R.K.; Wojcik, S.
- Book ID
- 123488747
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 427 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0304-3835
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Tamoxifen (TX) and toremifene (TO) enhanced the lysis of P8 I 5 mastocytoma cells in vitro by syngeneic DBAZ spleen cells that have been activated by human recombinant interleukin-2 (IL-2) for 6 days (lymphokine-activated killer [LAK] cells). Similarly, enhanced tumor suppression occurred when TXor
## Abstract A recently advanced generalization is that a sialomucin coat surrounding tumour cells protects them from immunological surveillance. We have therefore studied the effects of neuraminidase (sialidase) on the immunolysis of P815 mastocytoma cells by sensitized spleen cells, __in vitro__,