๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Inhibitors of Farnesyltransferase: A Rational Approach to Cancer Chemotherapy?

โœ Scribed by Ian M. Bell


Publisher
John Wiley and Sons
Year
2004
Weight
48 KB
Volume
35
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Biochemical approaches to the combinatio
โœ Alan C. Sartorelli; Charles W. Shansky; Martin Rosman ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 336 KB ๐Ÿ‘ 2 views

The employment of biochemical concepts to select drugs for use in the treatment of colorectal cancer is advocated. It is stressed that new drug mixtures, even those employing agents inactive alone, with unique mechanisms of action may be fashioned through biochemical design. Following delineation of

Inhibitors of cytochrome P450 catalyzed
โœ Gyรถrgy M. Keserรผ; Istvรกn Kolossvรกry; Istvรกn Szรฉkely ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 329 KB

The inhibition of cytochrome P450 mediated oxidative metabolism affected by methylenedioxyphenyl synergists was studied by theoretical methods. Binding w ลฝ . conformations of safrole-based inhibitors piperonyl butoxide PBO , safrole, and x izosafrole were obtained by the recently developed low-mode

Rational approach to implementation of p
โœ Rou Wang; Arul M. Chinnaiyan; Rodney L. Dunn; Kirk J. Wojno; John T. Wei ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 168 KB

## Abstract ## BACKGROUND: Prostate cancer antigen 3 (__PCA3__) encodes a prostateโ€specific messenger ribonucleic acid (mRNA) that serves as the target for a novel urinary molecular assay for prostate cancer detection. The objective of the current study was to evaluate the ability of PCA3, added t

A Rational Approach to Selective Recogni
โœ Jik Chin; Christian Walsdorff; Brent Stranix; Jinho Oh; Hyun Jei Chung; Su-Moon ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 121 KB ๐Ÿ‘ 2 views

Over the past several decades there has been considerable interest in developing receptors for NH 4 . Such receptors are desirable as sensors in clinical analysis and in environmental chemistry. For example, concentrations of urea or creatinine in biological samples can be determined indirectly by