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Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway

✍ Scribed by Lu, Hao; Tonge, Peter J.


Book ID
120554174
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
1019 KB
Volume
41
Category
Article
ISSN
0001-4842

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Systematic Synthesis of Inhibitors of th
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## Abstract L‐Heptoses (L‐__glycero__‐D‐__manno__‐heptopyranoses) are constituents of the inner core of lipolysaccharide (LPS), a molecule playing key roles in the mortality of many infectious diseases as well as in the virulence of many human pathogens. The inhibition of the first enzymes of the b