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Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS

✍ Scribed by Giuseppe Leone; Maria Teresa Voso; Luciana Teofili; Michael Lübbert

Book ID
117792982
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
308 KB
Volume
109
Category
Article
ISSN
1090-2341

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## Abstract The homeobox gene __PROX1__ is related to the __Drosophila prospero__ gene, which is expressed in the developing central nervous system and lens‐secreting cone cells. We found that the __PROX1__ gene had missense and nonsense mutations in 4 of 29 hematologic cell lines analyzed. Decreas