Inhibitors of Adenosine Deaminase and the Development of Antiviral Agents
β Scribed by SEYMOUR S. COHEN
- Book ID
- 118722574
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 598 KB
- Volume
- 451
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Reaction of triethyl ortho[^14^C]formate (2) with 2βaminoβ1β(5βaminoβ1Hβimidazolβ4βyl)ethanone dihydrochloride (1) in the presence of molecular sieves 4A gave 6,7βdihydro[5β^14^C]imidazo[4,5βd][1,3]diazepinβ8(3H)βone hydrochloride monodimethyl sulfoxide (3) (radiochemical yield, 60%). T
Adenosine deaminase (ADA) is an enzyme of the purine metabolism which catalyzes the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. This ubiquitous enzyme has been found in a wide variety of microorganisms, plants, and invertebrates. In addition, i