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Inhibitors of adenosine catabolism improve recovery of dog myocardium after ischemia

✍ Scribed by Joseph R. Koke; Ling Min Fu; Dandan Sun; Donna M. Vaughan; Neville Bittar


Publisher
Springer
Year
1989
Tongue
English
Weight
492 KB
Volume
86
Category
Article
ISSN
0300-8177

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Mioflazine, a nucleoside transport inhibitor, was given PO to dogs at doses of 0.04-10 mg/kg. Sixteen hour polygraphic sleep recordings were made and analysis and sleep stage classification was done by computer. Mioflazine decreased wakefulness and increased slow wave sleep, but did not affect the l