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Inhibition of γ-glutamyl transpeptidase decreases amino acid uptake in human keratinocytes in culture

✍ Scribed by Juan R. Viña; Pilar Blay; Ana Ramirez; Antonio Castells; José Viña

Book ID
117980335
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
258 KB
Volume
269
Category
Article
ISSN
0014-5793

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Decreased L system amino acid transport
Decreased L system amino acid transport and decreased gamma-glutamyl transpeptidase are independent processes in human chronic lymphocytic leukemia B-lymphocytes
✍ Timothy J. Woodlock; Richard Brown; Matthew Mani; Lisa Pompeo; Howard Hoffman; G 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 547 KB

The L system of amino acid transport is markedly diminished in chronic lymphocytic leukemia (CLL) B-lymphocytes, with a maximal velocity less than 15% that of normal B-lymphocytes. Another membrane-associated function, the activity of the ectoenzyme, gamma-glutamyl transpeptidase (GGT), is diminishe