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Inhibition of γ-endorphin generating endopeptidase activity of rat brain by peptides: Structure activity relationship

✍ Scribed by Jos L.M. Lebouille; Wout H. Visser; Rudi W. Hendriks; Jan W. Van Nispen; Henk M. Greven; J.Peter H. Burbach

Book ID
115758799
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
373 KB
Volume
133
Category
Article
ISSN
0006-291X

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Quantitation of the endopeptidase activi
Quantitation of the endopeptidase activity generating γ-endorphin from β-endorphin in rat brain synaptic membranes by a radiometric assay
✍ Jos L.M. Lebouille; J.Peter H. Burbach; E.Ronald de Kloet 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 768 KB

gamma-Endorphin is a naturally occurring biologically active peptide that is produced by an endopeptidase activity cleaving its precursor beta-endorphin. This enzyme was termed gamma-endorphin generating enzyme (gamma-EGE). In order to quantitate gamma-EGE activity by means of a simple and sensitive