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Inhibition of β-catenin-mediated transactivation by flavanone in AGS gastric cancer cells

✍ Scribed by Chi Hoon Park; Eun Ryeong Hahm; Ju Hyung Lee; Kyung Chae Jung; Chul Hak Yang

Book ID
116290434
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
340 KB
Volume
331
Category
Article
ISSN
0006-291X

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## Abstract The loss of E‐cadherin expression and the translocation of β‐catenin to the nucleus are frequently associated with the metastatic conversion of epithelial cells. In the nucleus, β‐catenin binds to the TCF/LEF‐1 (T‐cell factor/ lymphoid enhancer factor) transcription factor family result