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Inhibition of β-amyloid production by nifedipine

✍ Scribed by Lovell, Mark A.; Fister, Shuling X.; Lynn, Bert C.

Book ID
123113389
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
45 KB
Volume
6
Category
Article
ISSN
1552-5260

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## Abstract The human amyloid precursor protein (APP) is processed by the nonamyloidogenic and the amyloidogenic catabolic pathways. The sequential cleavage of APP by the β‐ and γ‐secretase activities, known as the amyloidogenic processing of APP, leads to the formation of the amyloid‐β peptide (Aβ