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Inhibition of VCAM-1 Expression in Endothelial Cells by Reconstituted High Density Lipoproteins

✍ Scribed by Laura Calabresi; Guido Franceschini; Cesare R. Sirtori; Anna De Palma; Marina Saresella; Pasquale Ferrante; Donatella Taramelli


Book ID
115580808
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
106 KB
Volume
238
Category
Article
ISSN
0006-291X

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Endothelial cells, as they normally exist in the vasculature as quiescent cells, perform several functions. In an inflammatory response, endothelial cells are activated to up-regulate a number of genes, including E-selectin (ELAM-l), VCAM-1, ICAM-1, interleukin (IL)-l, IL-8 and plasminogen activator