𝔖 Bobbio Scriptorium
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Inhibition of two homeotic mutants ofDrosophila by 5-bromodeoxyuridine and fluorouracil

✍ Scribed by Ibars, George C. ;Selick, Harold E. ;Kauffman, Stuart A.

Book ID
102336294
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
451 KB
Volume
216
Category
Article
ISSN
0022-104X

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✦ Synopsis

Abstract

Nasobemia (Ns) and spineless‐aristapedia (ss^a40a^) are dominant and recessive homeotic mutants of Drosophila which convert parts of the antenna to leg structures. Exposure of Ns and ss^a40a^ larvae to half‐lethal concentrations of 5‐bromodeoxyuridine (BUdR) and flourouracil (FU) together or separately during the presumptive time of gene action suppresses the expressivity and penetrance of the mutants.

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Inhibition of 5 - fluorouracil-induced o
Inhibition of 5 - fluorouracil-induced ocular irritation by ocular ice packs
✍ Charles L. Loprinzi; Donald B. Wender; Michael H. Veeder; Judith R. O'Fallon; Na πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 382 KB

Background. This clinical trial was developed to determine whether ocular ice pack therapy would decrease 5-fluorouracil(5-FU)-induced ocular toxicity. Methods. Sixty-two patients who suffered from 5-FU-induced ocular toxicity, and were scheduled to receive another cycle of the chemotherapy that ca