Production of the antiviral cytokine, tumor necrosis factor-a is increased in chronic hepatitis B virus infection, and clinical studies of tumor necrosis factor-a have indicated a proviral effect at higher doses. To determine whether this might be related to abnormal cell surface tumor necrosis fact
✦ LIBER ✦
Inhibition of tumour necrosis factor-α in patients with chronic hepatitis C infection
✍ Scribed by C. Zavos; J. Kountouras; N. Zavos; D. Chatzopoulos
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 47 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0770-3198
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## Abstract Cytokines play a key role in the regulation of immune responses. In hepatitis C virus infection (HCV), the production of inappropriate cytokine levels appears to contribute to viral persistence and to affect response to therapy. Cytokine genes are polymorphic at specific sites, and cert