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Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by antisense oligonucleotides

โœ Scribed by Biddanda C. Ponnappa; Yedy Israel; Maria Aini; Feng Zhou; Rachel Russ; Qing-na Cao; Yiyang Hu; Raphael Rubin


Book ID
113487457
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
341 KB
Volume
69
Category
Article
ISSN
0006-2952

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## Abstract ## Background Fulminant liver failure can cause extreme mortality due to the lack of effective and targeting therapeutics for the disease. Novel therapeutics using antisense technology require an efficient and safe delivery system with Kupffer cell targeting ability. ## Methods We ex