We report on the inhibition of wound implantation by TA3Ha mammary carcinoma cells by Arg-Gly-Asp containing proteins and peptides using a hepatic wedge resection model. Intravenously injected TA3Ha cells rarely form tumor in the liver of syngeneic mice, but after hepatic wedge resection, 45% (107/2
Inhibition of tumor implantation at sites of trauma by plasminogen activators
โ Scribed by M. Satya Murthy; Louis J. Summaria; Richard J. Miller; Tamara B. Wyse; Robert A. Goldschmidt; Edward F. Scanlon
- Book ID
- 102672136
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 641 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Angiostatin is a tumor-derived angiogenesis inhibitor consisting of an internal fragment of plasminogen. Little is known about the production of angiostatin by human tumors. In this study, we examined the in vitro angiostatingenerating capacities of a panel of human tumor cell lines (total n โซุโฌ 75)
The mechanism by which intravesical recombinant tissue plasminogen activator (rTPA) prevents tumor cell adherence to injured bladder surfaces, and the optimal parameters for the in vivo use of rTPA for adherence prevention, were evaluated. Intravesical rTPA decreased tumor cell adherence to sites of