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Inhibition of tumor cell transplantability by iron and copper complexes of 5-substituted 2-formylpyridine thiosemicarbazones

✍ Scribed by Antholine, William E.; Knight, Judith M.; Petering, David H.


Book ID
124059534
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
412 KB
Volume
19
Category
Article
ISSN
0022-2623

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The purpose of this study was to evaluate the mechanism by which 2-acetylpyrazine-4 N-substituted thiosemicarbazone copper II complexes mediate their cytotoxicity. These compounds were shown to be cytotoxic to a variety of human and rodent tumors in cell culture and are potent cytocidal agents as de