Inhibition of transcription factor nuclear factor-κB by a mutant inhibitor-κBα attenuates resistance of human head and neck squamous cell carcinoma to TNF-α caspase-mediated cell death

Inhibition of growth and survival of hum

Inhibition of growth and survival of human head and neck squamous cell carcinoma cells by curcumin via modulation of nuclear factor-κB signaling

✍ Sita Aggarwal; Yasunari Takada; Sujay Singh; Jeffrey N. Myers; Bharat B. Aggarwa 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 971 KB

## Abstract Increased expression of proinflammatory and proangiogenic factors are associated with aggressive tumor growth and decreased survival of patients with head and neck squamous cell carcinoma (HNSCC). In as much as genes that are regulated by nuclear factor NF‐κB suppress apoptosis, induce