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Inhibition of the Uptake of Biogenic Amines into Mast Cells by Tricyclic Psychoactive Drugs

✍ Scribed by Frisk-Holmberg, Marianne

Book ID
114866108
Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
452 KB
Volume
85
Category
Article
ISSN
0001-6772

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Uptake inhibition of biogenic amines by
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✍ A. Randrup; C. Bræstrup 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 615 KB

The dopamine theory of depression was studied by assessing the effect of antidepressant drugs on uptake of dopamine, noradrenaline, and serotonin in synaptosomes from rat brain. Five newer drugs--butriptyline, maprotiline, trimipramine, iprindole, and mianserine--exhibited rather potent inhibition o