Inhibition of the proliferation of human periodontal ligament fibroblasts by hyaluronidase
โ Scribed by Kotaro Tanimoto; Yuki Nakatani; Nobuaki Tanaka; Masashi Ueki; Tamami Yanagida; Reiko Kitamura; Yuki Tanne; Yu Yu Lin; Ryo Kunimatsu; Kazuo Tanne
- Book ID
- 113466008
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 709 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0003-9969
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The capacity of human periodontal ligament fibroblasts (PLF) to proliferate in response to mechanical force plays a critical role in orthodontic tooth movement. Extensive research has not fully revealed the mechanisms by which the PLF respond to mechanical force. The responses to force
Numerous studies have shown that hydrogen peroxide (H 2 O 2 ) inhibits proliferation and osteoblastic differentiation in bone-like cells. Human periodontal ligament fibroblasts (PLF) are capable of differentiating into osteoblasts and are exposed to oxidative stress during periodontal inflammation.