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Inhibition of the Progression of Multiple Sclerosis by Linomide Is Associated with Upregulation of CD4+/CD45RA+Cells and Downregulation of CD4+/CD45RO+Cells

✍ Scribed by Dan Lehmann; Dimitrios Karussis; Rachel Mizrachi-Koll; Anders S. Linde; Oded Abramsky

Book ID
112241069
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
137 KB
Volume
85
Category
Article
ISSN
1090-2341

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Decrease of CD4+ CD45+ T-cells in chroni
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✍ M. Zaffaroni; S. Rossini; A. Ghezzi; R. Parma; C. L. Cazzullo πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 347 KB

Circulating lymphocyte subpopulations defined by anti-CD45 and other more common T-cell-specific monoclonal antibodies were analysed in 77 patients with multiple sclerosis and 38 healthy controls. A selective decrease of CD4+CD45+ cell percentages and absolute numbers in chronic-progressive patients