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Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells

✍ Scribed by Yi, Yong Weon; Hong, Wooyoung; Kang, Hyo Jin; Kim, Hee Jeong; Zhao, Wenjing; Wang, Antai; Seong, Yeon-Sun; Bae, Insoo


Book ID
120230713
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2013
Tongue
English
Weight
412 KB
Volume
17
Category
Article
ISSN
1582-1838

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Inhibitors of the PI3-kinase/Akt pathway
✍ Therese H HemstrΓΆm; Margareta SandstrΓΆm; Boris Zhivotovsky πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 696 KB

## Abstract Non‐small cell lung cancer cells (NSCLC) are more resistant to anticancer treatment as compared with other types of cancer cells. Recently (HemstrΓΆm __et al__., Exp Cell Res 2005;305:200–13) we showed that apoptosis of U1810 NSCLC cells induced by the staurosporine analog PKC 412 correl