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Inhibition of the human complement component C4 by Flavivirus non-structural protein NS1

✍ Scribed by Panisadee Avirutnan; Anja Fuchs; Richard E. Hauhart; Pawit Somnuke; Soonjeon Youn; Michael S. Diamond; John P. Atkinson


Book ID
113805124
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
73 KB
Volume
47
Category
Article
ISSN
0161-5890

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## Abstract The ability of gold sodium thiomalate to inhibit production of the second complement component (C2) by monocytes stimulated by a lymphokine (monocyte complement stimulator) is demonstrated. This gold salt inhibits C2 production irreversibly if monocytes are incubated with it before or d